1456542-69-0
1456542-69-0 structure
- Name: BRD-7880
- Chemical Name: BRD-7880
- CAS Number: 1456542-69-0
- Molecular Formula: C32H38N4O7
- Molecular Weight: 590.677
- Create Date: 2020-01-12 08:20:50
- Modify Date: 2024-09-13 18:40:30
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A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM); is far more selective than tozasertib (VX-680), substantially inhibiting (to < 25% control activity) only AURKB and AURKC in a panel of 308 kinases.
| Name | BRD-7880 |
|---|
| Description | A potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM); is far more selective than tozasertib (VX-680), substantially inhibiting (to < 25% control activity) only AURKB and AURKC in a panel of 308 kinases. |
|---|---|
| References | References 1. Yu C, et al. Nat Biotechnol. 2016 Apr;34(4):419-23. View Related Products by Target Aurora Kinase |
| Molecular Formula | C32H38N4O7 |
|---|---|
| Molecular Weight | 590.677 |