Name | VU 6001966 |
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Description | A potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM; shows no inhibition for mGlu3 (IC50>30 uM); represents an exciting lead series for potential mGlu2 PET tracer development. |
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References | References 1. Bollinger KA, et al. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924. View Related Products by Target mGluR |
Molecular Formula | C17H15FN4O2 |
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Molecular Weight | 326.331 |