2215049-71-9
2215049-71-9 structure
- Name: LIMK1 and 2 dual inhibitor
- Chemical Name: LIMK1 and 2 dual inhibitor
- CAS Number: 2215049-71-9
- Molecular Formula: C28H21F3N6O3S2
- Molecular Weight: 610.63
- Create Date: 2020-01-11 17:53:39
- Modify Date: 2024-01-10 12:39:55
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LIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM); inhibits p-c-ofilin at Ser3 site, suppresses cell proliferation of MV-411 cell of with IC50 of 1-5 uM.
| Name | LIMK1 and 2 dual inhibitor |
|---|
| Description | LIMK1 and 2 dual inhibitor is a potent, selective LIMK1/2 inhibitor with IC50 of <10 nM for both, 15-fold selectivity over B-Raf (IC50=10-100 nM); inhibits p-c-ofilin at Ser3 site, suppresses cell proliferation of MV-411 cell of with IC50 of 1-5 uM. |
|---|---|
| References | References 1. US Patent WO 2018055097. View Related Products by Target LIM Kinase (LIMK) |
| Molecular Formula | C28H21F3N6O3S2 |
|---|---|
| Molecular Weight | 610.63 |