2249799-35-5

2249799-35-5 structure

Name: (3S,5R)-Fluvastatin D6 sodium
Chemical Name: (3S,5R)-Fluvastatin D6 sodium
CAS Number: 2249799-35-5
Molecular Formula: C₂₄H₁₉D₆FNNaO₄
Molecular Weight: 439.48
Catalog: Signaling Pathways Metabolic Enzyme/Protease HMG-CoA Reductase (HMGCR)
Create Date: 2020-01-23 12:52:51
Modify Date: 2024-01-10 17:02:12
(3S,5R)-Fluvastatin D6 sodium is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1]

Name	(3S,5R)-Fluvastatin D6 sodium

Description	(3S,5R)-Fluvastatin D6 sodium is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1]
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)
References	[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.

Molecular Formula	C₂₄H₁₉D₆FNNaO₄
Molecular Weight	439.48