1198784-72-3

1198784-72-3 structure

Name: BI 653048
Chemical Name: BI 653048
CAS Number: 1198784-72-3
Molecular Formula: C₂₃H₂₅F₄N₃O₄S
Molecular Weight: 515.52
Catalog: Signaling Pathways GPCR/G Protein Glucocorticoid Receptor
Create Date: 2020-01-23 16:59:51
Modify Date: 2024-01-08 18:42:59
BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects[1]. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[2].

Name	BI 653048

Description	BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects[1]. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
Target	IC50: Glucocorticoid (GC)[1]
References	[1]. Reeves JT, et al. Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.J Org Chem. 2013 Apr 19;78(8):3616-35. [2]. Montse Llinas-Brunet, et al. Latest bibliographic data on file with the International Bureau

Molecular Formula	C₂₃H₂₅F₄N₃O₄S
Molecular Weight	515.52