2378261-87-9
2378261-87-9 structure
- Name: K-Ras ligand-Linker Conjugate 3
- Chemical Name: K-Ras ligand-Linker Conjugate 3
- CAS Number: 2378261-87-9
- Molecular Formula: C49H65N7O10S
- Molecular Weight: 944.15
- Catalog: Research Areas Cancer
- Create Date: 2020-01-23 20:15:51
- Modify Date: 2024-06-15 12:28:38
-
K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1].
| Name | K-Ras ligand-Linker Conjugate 3 |
|---|
| Description | K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2. |
| Molecular Formula | C49H65N7O10S |
|---|---|
| Molecular Weight | 944.15 |
| Hazard Codes | Xi |
|---|