K-Ras ligand-Linker Conjugate 3

Modify Date: 2024-06-15 12:28:38

K-Ras ligand-Linker Conjugate 3 Structure
K-Ras ligand-Linker Conjugate 3 structure
Common Name K-Ras ligand-Linker Conjugate 3
CAS Number 2378261-87-9 Molecular Weight 944.15
Density N/A Boiling Point N/A
Molecular Formula C49H65N7O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of K-Ras ligand-Linker Conjugate 3


K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1].

 Names

Name K-Ras ligand-Linker Conjugate 3

 K-Ras ligand-Linker Conjugate 3 Biological Activity

Description K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1].
Related Catalog
References

[1]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2.

 Chemical & Physical Properties

Molecular Formula C49H65N7O10S
Molecular Weight 944.15

 Safety Information

Hazard Codes Xi