K-Ras ligand-Linker Conjugate 3 structure
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Common Name | K-Ras ligand-Linker Conjugate 3 | ||
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CAS Number | 2378261-87-9 | Molecular Weight | 944.15 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C49H65N7O10S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of K-Ras ligand-Linker Conjugate 3K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1]. |
Name | K-Ras ligand-Linker Conjugate 3 |
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Description | K-Ras ligand-Linker Conjugate 3 (Compound 001371) incorporates a ligand for FAK (a KRas recruiting moiety), and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 3 can be extensively used for PROTAC-mediated protein degradation[1]. |
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Related Catalog | |
References |
[1]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2019195609A2. |
Molecular Formula | C49H65N7O10S |
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Molecular Weight | 944.15 |
Hazard Codes | Xi |
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