2097509-36-7

2097509-36-7 structure

Name: Thalidomide-NH-PEG2-C2-NH2 TFA
Chemical Name: Thalidomide-NH-PEG2-C2-NH2 TFA
CAS Number: 2097509-36-7
Molecular Formula: C₂₁H₂₅F₃N₄O₈
Molecular Weight: 518.44
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-01-23 11:10:51
Modify Date: 2024-01-09 22:14:31
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

Name	Thalidomide-NH-PEG2-C2-NH2 TFA

Description	Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Molecular Formula	C₂₁H₂₅F₃N₄O₈
Molecular Weight	518.44

Hazard Codes	Xi