2143964-62-7

2143964-62-7 structure
2143964-62-7 structure
  • Name: Biotin-PEG8-acid
  • Chemical Name: Biotin-PEG8-acid
  • CAS Number: 2143964-62-7
  • Molecular Formula: C29H53N3O12S
  • Molecular Weight: 667.81
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-13 09:25:45
  • Modify Date: 2024-01-10 17:02:51
  • Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG8-acid
Synonyms MFCD26127802
Description Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula C29H53N3O12S
Molecular Weight 667.81