2086688-98-2

2086688-98-2 structure
2086688-98-2 structure
  • Name: t-Boc-aminooxy-PEG5-propargyl
  • Chemical Name: Boc-aminooxy-PEG5-propargyl
  • CAS Number: 2086688-98-2
  • Molecular Formula: C18H33NO8
  • Molecular Weight: 391.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-08 20:15:26
  • Modify Date: 2024-01-10 12:07:10
  • Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Boc-aminooxy-PEG5-propargyl
Synonyms MFCD30723288
Description Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

Molecular Formula C18H33NO8
Molecular Weight 391.46