2243566-45-0

2243566-45-0 structure

Name: m-PEG3-amido-C3-triethoxysilane
Chemical Name: m-PEG3-amido-C3-triethoxysilane
CAS Number: 2243566-45-0
Molecular Formula: C₁₇H₃₇NO₇Si
Molecular Weight: 395.56
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-13 13:31:20
Modify Date: 2024-01-10 19:10:13
m-PEG3-amido-C3-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	m-PEG3-amido-C3-triethoxysilane

Description	m-PEG3-amido-C3-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.