2133360-04-8

2133360-04-8 structure

Name: Pomalidomide-PEG1-azide
Chemical Name: Pomalidomide-PEG1-azide
CAS Number: 2133360-04-8
Molecular Formula: C₁₇H₁₆N₆O₆
Molecular Weight: 400.35
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-04-10 21:12:57
Modify Date: 2024-07-19 10:09:11
Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].

Name	Pomalidomide-PEG1-azide

Description	Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₁₇H₁₆N₆O₆
Molecular Weight	400.35

Hazard Codes	Xi