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2055198-02-0

2055198-02-0 structure
2055198-02-0 structure
  • Name: 3,4-Dibromo-Mal-PEG8-t-butyl ester
  • Chemical Name: 3,4-Dibromo-Mal-PEG8-Boc
  • CAS Number: 2055198-02-0
  • Molecular Formula: C27H45Br2NO12
  • Molecular Weight: 735.45
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:52:12
  • Modify Date: 2024-01-03 12:36:16
  • 3,4-Dibromo-Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3,4-Dibromo-Mal-PEG8-Boc
Description 3,4-Dibromo-Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H45Br2NO12
Molecular Weight 735.45