2253965-03-4

2253965-03-4 structure

Name: Aminooxy-amido-PEG4-propargyl
Chemical Name: Aminooxy-amido-PEG4-propargyl
CAS Number: 2253965-03-4
Molecular Formula: C₁₃H₂₄N₂O₆
Molecular Weight: 304.34
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-06-01 22:36:26
Modify Date: 2024-01-09 18:34:18
Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Aminooxy-amido-PEG4-propargyl

Description	Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.