2144777-83-1

2144777-83-1 structure
2144777-83-1 structure
  • Name: Azidoethyl-PEG2-t-Butyl ester
  • Chemical Name: Azidoethyl-SS-PEG2-Boc
  • CAS Number: 2144777-83-1
  • Molecular Formula: C13H25N3O4S2
  • Molecular Weight: 351.49
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:16:12
  • Modify Date: 2024-01-08 12:32:53
  • Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azidoethyl-SS-PEG2-Boc
Description Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H25N3O4S2
Molecular Weight 351.49