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2144775-48-2

2144775-48-2 structure
2144775-48-2 structure
  • Name: Biotin-PEG6-Thalidomide
  • Chemical Name: Biotin-PEG6-Thalidomide
  • CAS Number: 2144775-48-2
  • Molecular Formula: C37H53N5O12S
  • Molecular Weight: 791.91
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:40:14
  • Modify Date: 2024-01-08 15:36:08
  • Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name Biotin-PEG6-Thalidomide
Synonyms MFCD31561114
Description Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Molecular Formula C37H53N5O12S
Molecular Weight 791.91

Chemsrc provides CAS#:2144775-48-2 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2144775-48-2 | Chemsrc address: https://www.chemsrc.com/en/baike/1565154.html

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