2107273-44-7

2107273-44-7 structure
2107273-44-7 structure
  • Name: Bis-(N,N'-carboxyl-PEG4)-Cy5
  • Chemical Name: Bis-(N,N'-carboxyl-PEG4)-Cy5
  • CAS Number: 2107273-44-7
  • Molecular Formula: C47H67ClN2O12
  • Molecular Weight: 887.49
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:39:06
  • Modify Date: 2024-01-04 23:44:06
  • Bis-(N,N'-carboxyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-(N,N'-carboxyl-PEG4)-Cy5
Description Bis-(N,N'-carboxyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C47H67ClN2O12
Molecular Weight 887.49