Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bis-propargyl-PEG11
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

1351373-49-3

1351373-49-3 structure

1351373-49-3 structure

Name: Bis-propargyl-PEG12
Chemical Name: Bis-propargyl-PEG11
CAS Number: 1351373-49-3
Molecular Formula: C₂₈H₅₀O₁₂
Molecular Weight: 578.69
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-03 18:37:13
Modify Date: 2024-01-28 17:42:53
Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-propargyl-PEG11

Description	Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₈H₅₀O₁₂
Molecular Weight	578.69