1351373-49-3

1351373-49-3 structure
1351373-49-3 structure
  • Name: Bis-propargyl-PEG12
  • Chemical Name: Bis-propargyl-PEG11
  • CAS Number: 1351373-49-3
  • Molecular Formula: C28H50O12
  • Molecular Weight: 578.69
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-03 18:37:13
  • Modify Date: 2024-01-28 17:42:53
  • Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-propargyl-PEG11
Description Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C28H50O12
Molecular Weight 578.69