1052207-59-6

1052207-59-6 structure

1052207-59-6 structure

Name: Boc-NH-PEG8-CH2CH2NH2
Chemical Name: Boc-NH-PEG8-CH2CH2NH2
CAS Number: 1052207-59-6
Molecular Formula: C₂₃H₄₈N₂O₁₀
Molecular Weight: 512.63
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:42:31
Modify Date: 2024-01-16 19:37:44
Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG8-CH2CH2NH2
Synonyms	MFCD31656919

Description	Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₄₈N₂O₁₀
Molecular Weight	512.63

Hazard Codes	Xi