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1884349-58-9

1884349-58-9 structure
1884349-58-9 structure
  • Name: Diazo Biotin-PEG3-alkyne
  • Chemical Name: Diazo Biotin-PEG3-alkyne
  • CAS Number: 1884349-58-9
  • Molecular Formula: C39H53N7O9S
  • Molecular Weight: 795.94
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:43:52
  • Modify Date: 2024-01-21 11:06:22
  • Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Diazo Biotin-PEG3-alkyne
Synonyms MFCD28505544
Description Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C39H53N7O9S
Molecular Weight 795.94