2378590-46-4

2378590-46-4 structure
2378590-46-4 structure
  • Name: Fmoc-NH-PEG15-CH2CH2COOH
  • Chemical Name: Fmoc-NH-PEG15-CH2CH2COOH
  • CAS Number: 2378590-46-4
  • Molecular Formula: C48H77NO19
  • Molecular Weight: 972.12
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 09:50:25
  • Modify Date: 2024-01-09 22:49:36
  • Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Fmoc-NH-PEG15-CH2CH2COOH
Description Fmoc-NH-PEG15-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C48H77NO19
Molecular Weight 972.12
Hazard Codes Xi