1372860-04-2

1372860-04-2 structure
1372860-04-2 structure
  • Name: m-PEG8-succinimidyl carbonate
  • Chemical Name: m-PEG8-succinimidyl carbonate
  • CAS Number: 1372860-04-2
  • Molecular Formula: C22H39NO13
  • Molecular Weight: 525.54
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:35:32
  • Modify Date: 2024-01-09 18:45:48
  • m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG8-succinimidyl carbonate
Synonyms MFCD31380405
Description m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H39NO13
Molecular Weight 525.54