2055023-14-6

2055023-14-6 structure

2055023-14-6 structure

Name: Mal-NH-PEG8-CH2CH2COOPFP ester
Chemical Name: Mal-NH-PEG8-CH2CH2COOPFP ester
CAS Number: 2055023-14-6
Molecular Formula: C₃₂H₄₃F₅N₂O₁₃
Molecular Weight: 758.68
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:19:45
Modify Date: 2024-01-31 17:34:20
Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-NH-PEG8-CH2CH2COOPFP ester
Synonyms	MFCD28385471

Description	Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₂H₄₃F₅N₂O₁₃
Molecular Weight	758.68

Hazard Codes	Xi