1262681-30-0

1262681-30-0 structure
1262681-30-0 structure
  • Name: Mal-PEG4-propargyl
  • Chemical Name: Mal-​PEG4-​propargyl
  • CAS Number: 1262681-30-0
  • Molecular Formula: C15H21NO6
  • Molecular Weight: 311.33
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:15:03
  • Modify Date: 2024-02-06 19:45:39
  • Mal-​PEG4-​propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-​PEG4-​propargyl
Description Mal-​PEG4-​propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H21NO6
Molecular Weight 311.33