Mal-PEG4-propargyl

Modify Date: 2024-02-06 19:45:39

Mal-PEG4-propargyl Structure
Mal-PEG4-propargyl structure
Common Name Mal-PEG4-propargyl
CAS Number 1262681-30-0 Molecular Weight 311.33
Density N/A Boiling Point N/A
Molecular Formula C15H21NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG4-propargyl


Mal-​PEG4-​propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-​PEG4-​propargyl

 Mal-PEG4-propargyl Biological Activity

Description Mal-​PEG4-​propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H21NO6
Molecular Weight 311.33