113387-03-4

113387-03-4 structure
113387-03-4 structure
  • Name: Mal-PEG5-mal
  • Chemical Name: Mal-PEG5-mal
  • CAS Number: 113387-03-4
  • Molecular Formula: C20H28N2O9
  • Molecular Weight: 440.44
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:36:31
  • Modify Date: 2024-01-09 15:44:45
  • Mal-PEG5-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG5-mal
Description Mal-PEG5-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C20H28N2O9
Molecular Weight 440.44