1380500-88-8

1380500-88-8 structure
1380500-88-8 structure
  • Name: Methyltetrazine-acid
  • Chemical Name: Methyltetrazine-acid
  • CAS Number: 1380500-88-8
  • Molecular Formula: C11H10N4O2
  • Molecular Weight: 230.22
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:14:02
  • Modify Date: 2024-01-16 19:34:53
  • Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyltetrazine-acid
Synonyms MFCD28334556
Description Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H10N4O2
Molecular Weight 230.22
Hazard Codes Xi