2093153-97-8

2093153-97-8 structure
2093153-97-8 structure
  • Name: N-(Amino-PEG4)-N-bis(PEG4-t-butyl ester)
  • Chemical Name: N-(Amino-PEG4)-N-bis(PEG4-Boc)
  • CAS Number: 2093153-97-8
  • Molecular Formula: C40H80N2O16
  • Molecular Weight: 845.07
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:57:27
  • Modify Date: 2024-01-09 17:27:14
  • N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Amino-PEG4)-N-bis(PEG4-Boc)
Synonyms MFCD30723262
Description N-(Amino-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C40H80N2O16
Molecular Weight 845.07