2353409-46-6

2353409-46-6 structure
2353409-46-6 structure
  • Name: N-(Boc-PEG2)-N-bis(PEG3-azide)
  • Chemical Name: N-(Boc-PEG2)-N-bis(PEG3-azide)
  • CAS Number: 2353409-46-6
  • Molecular Formula: C28H53N7O11
  • Molecular Weight: 663.76
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 22:57:57
  • Modify Date: 2024-01-09 10:01:57
  • N-(Boc-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Boc-PEG2)-N-bis(PEG3-azide)
Description N-(Boc-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C28H53N7O11
Molecular Weight 663.76