2107273-08-3

2107273-08-3 structure
2107273-08-3 structure
  • Name: N,N'-bis-(propargyl-PEG4)-Cy5 (chloride)
  • Chemical Name: N,N'-bis-(propargyl-PEG4)-Cy5
  • CAS Number: 2107273-08-3
  • Molecular Formula: C47H63ClN2O8
  • Molecular Weight: 819.46
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:01:04
  • Modify Date: 2024-01-02 12:48:12
  • N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N,N'-bis-(propargyl-PEG4)-Cy5
Description N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C47H63ClN2O8
Molecular Weight 819.46