Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (2-[2-(2-(2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy)-ethoxy)-ethoxy]-ethoxy)-acetic acid tert-butyl ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Tos-PEG6-CH2CO2tBu
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1949793-62-7

1949793-62-7 structure

1949793-62-7 structure

Name: Tos-PEG6-CH2CO2tBu
Chemical Name: Tos-PEG5-CH2COOtBu
CAS Number: 1949793-62-7
Molecular Formula: C₂₃H₃₈O₁₀S
Molecular Weight: 506.61
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:13:34
Modify Date: 2024-01-13 18:12:21
Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG5-CH2COOtBu
Synonyms	MFCD30828689

Description	Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₃₈O₁₀S
Molecular Weight	506.61