2101206-50-0

2101206-50-0 structure

2101206-50-0 structure

Name: Cyclooctyne-O-amido-PEG4-NHS ester
Chemical Name: Cyclooctyne-O-amido-PEG4-NHS ester
CAS Number: 2101206-50-0
Molecular Formula: C₂₅H₃₈N₂O₁₀
Molecular Weight: 526.58
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-08-10 19:18:35
Modify Date: 2024-01-09 10:55:44
Cyclooctyne-O-amido-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Cyclooctyne-O-amido-PEG4-NHS ester

Description	Cyclooctyne-O-amido-PEG4-NHS ester is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₂₅H₃₈N₂O₁₀
Molecular Weight	526.58