676657-00-4

676657-00-4 structure

Name: KYL TFA
Chemical Name: KYL peptide
CAS Number: 676657-00-4
Molecular Formula: C₇₄H₁₀₈N₁₄O₁₇
Molecular Weight: 1465.73
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Ephrin Receptor
Create Date: 2020-08-09 23:57:44
Modify Date: 2024-01-12 09:34:24
KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd=0.8 μM). KYL peptide inhibits EphA4-EphrinA5 interactions (IC50=6.34 μM). KYL peptide prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. KYL peptide also exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively).

Name	KYL peptide

Description	KYL peptide is an EphA4 receptor tyrosine kinase inhibitor (Kd=0.8 μM). KYL peptide inhibits EphA4-EphrinA5 interactions (IC50=6.34 μM). KYL peptide prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. KYL peptide also exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively).
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ephrin Receptor