2140807-42-5

2140807-42-5 structure

Name: (S,R,S)-AHPC-PEG3-propionic acid
Chemical Name: (S,R,S)-AHPC-PEG3-propionic acid
CAS Number: 2140807-42-5
Molecular Formula: C₃₂H₄₆N₄O₉S
Molecular Weight: 662.79
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-08-09 18:01:50
Modify Date: 2024-01-11 05:56:19
(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1].

Name	(S,R,S)-AHPC-PEG3-propionic acid

Description	(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
References	[1]. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.

Molecular Formula	C₃₂H₄₆N₄O₉S
Molecular Weight	662.79

Hazard Codes	Xi