- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Serelaxin
- Price: ￥Inquiry/250mg ￥Inquiry/100mg ￥Inquiry/1g
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- DC Chemicals Limited
- China
- Product Name: Serelaxin
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: RELAXIN H2 (HUMAN)
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
99489-94-8
99489-94-8 structure
- Name: Relaxin H2 (human) trifluoroacetate salt
- Chemical Name: Serelaxin
- CAS Number: 99489-94-8
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2020-08-11 16:09:08
- Modify Date: 2024-01-07 17:08:00
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Serelaxin (RLX-030), a recombinant form of human gene-2 relaxin targeting the RLN receptor, is a vasoactive peptide hormone with an antifibrotic activity[1][2][3].
| Name | Serelaxin |
|---|
| Description | Serelaxin (RLX-030), a recombinant form of human gene-2 relaxin targeting the RLN receptor, is a vasoactive peptide hormone with an antifibrotic activity[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vivo | Serelaxin (0.5 mg/kg per day, subcutaneous administration) produces 20 to 40 ng/mL of circulating hormone, which successfully prevents and reduces fibrosis progression in various experimental models of injury. The doses do not exhibit significant toxicity[1]. Serelaxin restores endothelial function by increasing nitric oxide (NO)-mediated relaxation but not endothelium-derived hyperpolarisation (EDH)[2]. Animal Model: Six- to 8-week-old male mice (on a 129sv or 129sv×C57B6J background, which were equally sensitive to tissue injury and fibrosis)[1]. Dosage: 0.5 mg/kg. Administration: Subcutaneous administration per day for 7 days. Result: Produced 20 to 40 ng/mL of circulating hormone. |
| References |
[3]. Serelaxin. |
| No Any Chemical & Physical Properties |