2341841-02-7

2341841-02-7 structure

Name: Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
Chemical Name: Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
CAS Number: 2341841-02-7
Molecular Formula: C₁₇H₁₉ClN₄O₆
Molecular Weight: 410.81
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-08-11 15:29:36
Modify Date: 2024-09-16 18:52:50
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].

Name	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Description	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952.

Molecular Formula	C₁₇H₁₉ClN₄O₆
Molecular Weight	410.81

Hazard Codes	Xi