Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Modify Date: 2024-09-16 18:52:50

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride structure	Common Name	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
	CAS Number	2341841-02-7	Molecular Weight	410.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₉ClN₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].

Name	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Description	Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952.

Molecular Formula	C₁₇H₁₉ClN₄O₆
Molecular Weight	410.81

Hazard Codes	Xi

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Use of Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Names

Biological Activity

Chemical & Physical Properties

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