1359968-33-4
1359968-33-4 structure
- Name: BW-759
- Chemical Name: BW-759
- CAS Number: 1359968-33-4
- Molecular Formula: C9H15N5O5
- Molecular Weight: 273.25
- Catalog: Signaling Pathways Anti-infection CMV
- Create Date: 2021-01-09 17:58:26
- Modify Date: 2024-01-31 10:15:38
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Ganciclovir (INN) is an antiviral medication used to treat or prevent cytomegalovirus (CMV) infections. Ganciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) gene UL97 during infection. Subsequently, cellular kinases catalyze the formation of ganciclovir diphosphate and ganciclovir triphosphate, which is present in 10-fold greater concentrations in CMV or herpes simplex virus (HSV)-infected cells than uninfected cells. A prodrug form with improved oral bioavailability (valganciclovir) has also been developed.
| Name | BW-759 |
|---|
| Description | Ganciclovir (INN) is an antiviral medication used to treat or prevent cytomegalovirus (CMV) infections. Ganciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) gene UL97 during infection. Subsequently, cellular kinases catalyze the formation of ganciclovir diphosphate and ganciclovir triphosphate, which is present in 10-fold greater concentrations in CMV or herpes simplex virus (HSV)-infected cells than uninfected cells. A prodrug form with improved oral bioavailability (valganciclovir) has also been developed. |
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| Molecular Formula | C9H15N5O5 |
|---|---|
| Molecular Weight | 273.25 |