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286369-38-8

286369-38-8 structure
286369-38-8 structure
  • Name: S 14506 hydrochloride
  • Chemical Name: S 14506 hydrochloride
  • CAS Number: 286369-38-8
  • Molecular Formula: C24H27ClFN3O2
  • Molecular Weight: 443.941
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2021-05-12 12:52:30
  • Modify Date: 2024-01-16 10:27:34
  • S-14506 hydrochloride is a potent 5-HT1A agonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent[1][2].

Name S 14506 hydrochloride
Synonyms S-14506 HYDROCHLORIDE
4-Fluoro-N-{2-[4-(7-methoxy-1-naphthyl)-1-piperazinyl]ethyl}benzamide hydrochloride (1:1)
MFCD00910294
Benzamide, 4-fluoro-N-[2-[4-(7-methoxy-1-naphthalenyl)-1-piperazinyl]ethyl]-, hydrochloride (1:1)
4-Fluoro-N-{2-[4-(7-methoxy-1-naphthyl)piperazin-1-yl]ethyl}benzamide hydrochloride (1:1)
4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride
Description S-14506 hydrochloride is a potent 5-HT1A agonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent[1][2].
Related Catalog
References

[1]. Francis C. Colpaert, et al. S 14506: A novel, potent, high-efficacy 5-HT1A agonist and potential anxiolytic agent. 1992, 21-48.

[2]. Protais P, et al. Dopamine receptor antagonist properties of S 14506, 8-OH-DPAT, raclopride and clozapine in rodents. Eur J Pharmacol. 1994 Dec 12;271(1):167-77.

Molecular Formula C24H27ClFN3O2
Molecular Weight 443.941
Exact Mass 443.177582