127457-61-8

127457-61-8 structure
127457-61-8 structure
  • Name: Benzyl-PEG3-methyl ester
  • Chemical Name: Benzyl-PEG3-methyl ester
  • CAS Number: 127457-61-8
  • Molecular Formula: C15H22O5
  • Molecular Weight: 282.33
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-07-27 20:11:07
  • Modify Date: 2024-01-17 15:13:36
  • Benzyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Benzyl-PEG3-methyl ester
Description Benzyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H22O5
Molecular Weight 282.33