1449202-44-1

1449202-44-1 structure

Name: Benzyl-PEG6-bromide
Chemical Name: Benzyl-PEG6-bromide
CAS Number: 1449202-44-1
Molecular Formula: C₁₉H₃₁BrO₆
Molecular Weight: 435.35
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-08-29 12:23:42
Modify Date: 2024-04-07 16:13:06
Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Benzyl-PEG6-bromide

Description	Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562