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1421701-68-9

1421701-68-9 structure
1421701-68-9 structure
  • Name: Biotin-PEG3-propargyl
  • Chemical Name: Biotin-PEG3-propargyl
  • CAS Number: 1421701-68-9
  • Molecular Formula: C19H31N3O5S
  • Molecular Weight: 413.53
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-13 15:07:01
  • Modify Date: 2024-04-07 16:29:58
  • Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG3-propargyl
Synonyms MFCD31922734
Description Biotin-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H31N3O5S
Molecular Weight 413.53