2093409-57-3

2093409-57-3 structure

Name: DBCO-PEG3-amine
Chemical Name: DBCO-PEG3-amine
CAS Number: 2093409-57-3
Molecular Formula: C₂₇H₃₃N₃O₅
Molecular Weight: 479.57
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-09-10 11:28:04
Modify Date: 2024-01-10 18:11:50
DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG3-amine

Description	DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562