145119-18-2

145119-18-2 structure
145119-18-2 structure
  • Name: N-Boc-PEG-t-butyl ester
  • Chemical Name: N-Boc-PEG-t-butyl ester
  • CAS Number: 145119-18-2
  • Molecular Formula: C14H27NO5
  • Molecular Weight: 289.37
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-16 11:30:20
  • Modify Date: 2024-01-20 12:16:54
  • N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Boc-PEG-t-butyl ester
Description N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H27NO5
Molecular Weight 289.37