1695856-63-3

1695856-63-3 structure
1695856-63-3 structure
  • Name: N-Ethyl-N-methylpropionamide-PEG1-Br
  • Chemical Name: N-Ethyl-N-methylpropionamide-PEG1-Br
  • CAS Number: 1695856-63-3
  • Molecular Formula: C8H16BrNO2
  • Molecular Weight: 238.12
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 12:29:25
  • Modify Date: 2024-01-16 17:05:33
  • N-Ethyl-N-methylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Ethyl-N-methylpropionamide-PEG1-Br
Description N-Ethyl-N-methylpropionamide-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H16BrNO2
Molecular Weight 238.12