- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Fmoc-AEEA
- Price: ￥Inquiry/1kg ￥Inquiry/1g ￥Inquiry/1mg ￥Inquiry/1ton
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
- Price: ￥958.0/1g ￥368.0/1g ￥288.0/250mg ￥1118.0/5g
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
- Price: ￥70.0/1g
- Purity: 99.0%
- Stocking Period: 20 Day
- Contact: Lihua Yang
- DC Chemicals Limited
- China
- Product Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
- Price: $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
166108-71-0
166108-71-0 structure
- Name: Fmoc-8-amino-3,6-dioxaoctanoic acid
- Chemical Name: [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid
- CAS Number: 166108-71-0
- Molecular Formula: C21H23NO6
- Molecular Weight: 385.410
- Catalog: Biochemical Amino acids and their derivatives FMOC-amino acid
- Create Date: 2018-12-16 20:50:15
- Modify Date: 2024-01-02 18:50:42
-
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Name | [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid |
|---|---|
| Synonyms |
2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
[2-[2-(Fmoc-Amino)ethoxy]ethoxy]acetic acid [2-[2-[(Fmoc-amino)ethoxy]ethoxy]acetic Acid 8-(Fmoc-amino)-3,6-dioxa-n-octanoic Acid {2-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-ethoxy]-ethoxy}-acetic acid Fmoc-NH-PEG2-CH2COOH MFCD01321015 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic acid [2-[2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]ethoxy]ethoxy]acetic Acid 2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid 8-[(9H-Fluoren-9-ylMethoxy)carbonylaMino]-3,6-dioxa-n-octanoic Acid Fmoc-mini-PEG Fmoc-AEEA |
| Description | Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 631.4±45.0 °C at 760 mmHg |
| Melting Point | 90-92℃ |
| Molecular Formula | C21H23NO6 |
| Molecular Weight | 385.410 |
| Flash Point | 335.6±28.7 °C |
| Exact Mass | 385.152527 |
| PSA | 94.09000 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.580 |
| Storage condition | -15°C |
| Hazard Codes | Xi |
|---|---|
| Safety Phrases | S22-S24/25 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
|
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166108-71-0 |
| Literature: Organic Letters, , vol. 7, # 9 p. 1699 - 1702 |
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166108-71-0 |
| Literature: Organic Letters, , vol. 7, # 9 p. 1699 - 1702 |
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166108-71-0 |
| Literature: Journal of the American Chemical Society, , vol. 133, # 32 p. 12382 - 12385 |
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166108-71-0 |
| Literature: Journal of the American Chemical Society, , vol. 133, # 32 p. 12382 - 12385 |
|
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166108-71-0 |
| Literature: Journal of the American Chemical Society, , vol. 133, # 32 p. 12382 - 12385 |
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166108-71-0 |
| Literature: Journal of the American Chemical Society, , vol. 133, # 32 p. 12382 - 12385 |
| Precursor 6 | |
|---|---|
| DownStream 1 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |