Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Levobupivacaine hydrochloride
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Levobupivacaine hydrochloride
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Levobupivacaine HCL
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DC Chemicals Limited
China
Product Name: Levobupivacaine HCL
Price: $250.0/100mg $600.0/250mg $1000.0/1g
Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Levobupivacaine hydrochloride
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Purity: 98.0%
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27262-48-2

27262-48-2 structure

27262-48-2 structure

Name: Levobupivacaine hydrochloride
Chemical Name: levobupivacaine hydrochloride (anhydrous)
CAS Number: 27262-48-2
Molecular Formula: C₁₈H₂₉ClN₂O
Molecular Weight: 324.889
Catalog: Biochemical Inhibitor Transmembrane Transporters Sodium Channel inhibitor
Create Date: 2018-07-02 08:51:40
Modify Date: 2024-01-02 07:18:39
Levobupivacaine Hcl is a local anaesthetic compound belonging to the amino amide group; long-acting local anesthetic.

Name	levobupivacaine hydrochloride (anhydrous)
Synonyms	levobupivacaine monohydrochloride Levobupivacainehydrochloride (S)-(-)-BUPIVACAINE HCL Levobupivacaine Hydrochloride L-BUPIVACAINE HYDROCHLORIDE L-(-)-Bupivacaine (S)-Bupivacaine hydrochloride (RS)-bupivacaine hydrochloride BUPIVACAINE HCL Levobupivacaine HCl bupivacaine.hydrochloride MFCD01704265 (-)-Bupivacaine hydrochloride Chirocaine (2S)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride (1:1) 2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, (2S)-, hydrochloride (1:1) 1-butyl-piperidine-2-carboxylic acid-(2,6-dimethyl-anilide),hydrochloride LEVAMISOLHCLSALT (2S)-1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride (1:1) (S)-(-)-Bupivacaine hydrochloride (S)-Bupivacaine (-)-Bupicaine Hydrochloride bupicainehydrochloride(-) Levobupivacaine (hydrochloride)

Description	Levobupivacaine Hcl is a local anaesthetic compound belonging to the amino amide group; long-acting local anesthetic.
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References	[1]. Burlacu CL, et al. Update on local anesthetics: focus on levobupivacaine. Ther Clin Risk Manag. 2008 Apr;4(2):381-92. [2]. Gulec D, et al. Intrathecal bupivacaine or levobupivacaine: which should be used for elderly patients? J Int Med Res. 2014 Apr;42(2):376-85.

Boiling Point	423.4ºC at 760 mmHg
Melting Point	254 °C (dec.)(lit.)
Molecular Formula	C₁₈H₂₉ClN₂O
Molecular Weight	324.889
Flash Point	209.9ºC
Exact Mass	324.196838
PSA	23.55000
LogP	4.74080
Vapour Pressure	2.24E-07mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK6120000

CHEMICAL NAME :: 2',6'-Pipecoloxylidide, 1-butyl-, hydrochloride, (-)-

CAS REGISTRY NUMBER :: 27262-48-2

LAST UPDATED :: 198209

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H28-N2-O.Cl-H

MOLECULAR WEIGHT :: 324.94

WISWESSER LINE NOTATION :: T6NTJ A4 BVMR B1 F1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5100 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 207 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 200,359,1972

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Hazard Codes	T+: Very toxic;Xn: Harmful;
Risk Phrases	R20/21/22
Safety Phrases	S22-S36/37/39-S45-S36/37-S53
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	TK6125000
HS Code	2942000000

HS Code	2942000000