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  • DC Chemicals Limited
  • China
  • Product Name: Exisulind
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

59973-80-7

59973-80-7 structure
59973-80-7 structure
  • Name: Exisulind
  • Chemical Name: sulindac sulfone
  • CAS Number: 59973-80-7
  • Molecular Formula: C20H17FO4S
  • Molecular Weight: 372.41
  • Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
  • Create Date: 2016-12-10 21:05:58
  • Modify Date: 2024-01-09 17:47:42
  • Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].

Name sulindac sulfone
Synonyms 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfonylphenyl)methylidene]inden-1-yl]acetic acid
Sulindac Sulfone
Description Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research[1].
Related Catalog
References

[1]. Aono Y, et al. Sulindac sulfone inhibits the mTORC1 pathway in colon cancer cells by directly targeting voltage-dependent anion channel 1 and 2. Biochem Biophys Res Commun. 2018 Nov 10;505(4):1203-1210.  

Melting Point 248-250ºC
Molecular Formula C20H17FO4S
Molecular Weight 372.41
Exact Mass 372.08300
PSA 79.82000
LogP 5.11240
Storage condition -20°C
RIDADR NONH for all modes of transport
WGK Germany 3
Precursor  1

DownStream  0