115199-84-3

115199-84-3 structure
115199-84-3 structure
  • Name: ICI 199,441 hydrochloride
  • Chemical Name: ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
  • CAS Number: 115199-84-3
  • Molecular Formula: C21H25Cl3N2O
  • Molecular Weight: 427.80
  • Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
  • Create Date: 2018-05-29 08:00:00
  • Modify Date: 2024-01-06 08:44:28
  • ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion[1].

Name ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
Synonyms ici 199,441
ici 199,441 hydrochloride
Description ICI 199441 is a potent and selective κ-opioid receptor agonist. ICI 199441 can improve heart resistance to ischemia/reperfusion[1].
Related Catalog
In Vivo ICI 199441 (Wistar rats, 0.1 mg/kg, IV, once) administered 15 min before ischemia produces a potent antiarrhythmic effect[1].
References

[1]. Tsibulnikov SY, et al. Prospects of Using of κ-Opioid Receptor Agonists U-50,488 and ICI 199,441 for Improving Heart Resistance to Ischemia/Reperfusion. Bull Exp Biol Med. 2015;159(6):718-721.

Boiling Point 532.8ºC at 760mmHg
Molecular Formula C21H25Cl3N2O
Molecular Weight 427.80
Flash Point 276ºC
Exact Mass 426.10300
PSA 23.55000
LogP 5.57130
Vapour Pressure 1.97E-11mmHg at 25°C
Precursor  2

DownStream  0