163163-24-4

163163-24-4 structure

Name: (-)-Chromanol 293B
Chemical Name: N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)-N-methylethanesulfonamide
CAS Number: 163163-24-4
Molecular Formula: C₁₅H₂₀N₂O₄S
Molecular Weight: 324.39500
Catalog: Research Areas Cardiovascular Disease
Create Date: 2016-11-08 10:00:25
Modify Date: 2024-01-09 11:50:30
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic[1].

Name	N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)-N-methylethanesulfonamide
Synonyms	Chromanol 293B HMS3267H14 HMR1556

Description	(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
Target	IKs[1]
In Vitro	(-)-Chromanol 293B selectively inhibits the KvLQT11＋minK ion channel complex[1].
References	[1]. Yang IC, et al. Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels. J Pharmacol Exp Ther. 2000;294(3):955-962.